Achondroplasia is a genetic disorder that inhibits endochondral ossification, resulting in disproportionate short stature and clinically significant medical complications. Vosoritide is a biologic ...

In a study published in Cell Research, researchers have identified a fibrous-layer resident subpopulation of P-SSCs labeled by Angptl7. They found that these cells are crucial for bone fracture repair ...

The skeleton is among the most commonly injured body tissues. Every year more than 16 million fractures of long bones occur in the United States. Fortunately, bone has excellent regenerative potential ...

Osteoblasts are the cells required for bone synthesis and mineralization, both during the initial formation of bone and during bone remodelling. These cells are present on the bone surface in the form ...

"Historically viewed as mainly a “wear and tear” condition, new insights suggest that OA may be part of an evolutionary, age-related biological process rather than mainly driven by mechanical damage." ...