No one can live without a heart pumping blood to the rest of the body. New research from the University of Missouri School of Medicine reveals more information about this vital function and how it’s ...

Now, in a study in zebrafish and human heart muscle cells, researchers show that a tiny deletion in the A-band of titin — the loss of just nine amino acids out of more than 27,000 to 35,000 amino ...

When a muscle contracts, the parts of a sarcomere "shorten" and come closer together. Each cardiac muscle cell can have over 5,000 sarcomeres, which compounds both the shortening and relaxation events ...

The human heart, often described as the body's engine, is a remarkable organ that tirelessly beats to keep us alive. At the core of this vital organ, intricate processes occur when it contracts, where ...

A protein-level tension sensor reveals how cell shape and sarcomere maturity determine where cardiomyocytes carry mechanical load.

SINGAPORE, 18 December 2023 – Scientists led by Duke-NUS Medical School in Singapore and the University of California, Los Angeles, (UCLA) in the United States have discovered a new control mechanism ...

Johns Hopkins Medicine scientists who arranged for 48 human bioengineered heart tissue samples to spend 30 days at the International Space Station report evidence that the low gravity conditions in ...

"The molecules essentially served as nano-defibrillators, getting these heart muscle cells to start beating," Beckham said. The ability to control cell-to-cell communication in muscle tissue could be ...