This image illustrates the process of gene transcription within a cell. The DNA double helix unwinds to expose a specific sequence, allowing RNA polymerase to synthesize a complementary pre-mRNA ...

Every living cell, from the simplest bacterium to a human neuron, relies on the same basic machinery to read, interpret, and use its DNA. This molecular machinery is so fundamental that life as we ...

A team led by researchers at UT Southwestern Medical Center has developed deep learning models to identify a simple set of rules that govern the activity of promoters—regions of DNA that initiate the ...

The human genome contains more than 20,000 genes. However, at any given time and in a given cell, only a fraction are active.

Transcription factors are central controllers of gene expression during development, directing cells towards specific fates by binding to regulatory DNA elements and recruiting chromatin-modifying ...

Transcription-coupled DNA damage repair represents a specialised branch of nucleotide excision repair that ensures rapid removal of lesions from the transcribed strand of active genes. When RNA ...

Elizabeth Campbell studies the molecular machinery that all living cells use to read and transcribe their genetic ...

While scientists have studied the molecular steps involved in gene expression for decades, many questions still remain about this fundamental process. To transcribe genes, RNA polymerase II (RNA Pol ...

Scientists at the Massachusetts Institute of Technology (MIT) have invented a new single-cell nascent RNA sequencing technique that lets them observe the timing of gene and enhancer activation in ...

(Alones Creative/iStock/Getty Images) One of the most iconic visual representations in biological science is the double helix ...