Scientists sorely need biomarkers of TDP-43 pathology, but finding reliable ones has been difficult. Now, two groups, working independently, have proposed a new angle—cryptic circular RNAs, or ...
Ask a clinician or a researcher about the blood-brain barrier (BBB) in Alzheimer’s disease, and you may hear about amyloid or leaky tight junctions. Fibronectin, a major scaffold protein, won’t ...
Neurodegenerative proteinopathies are characterized by misfolded proteins, which are thought to spread throughout the brain by coaxing healthy proteins to join their filament ranks. Faithful ...
Past AlzForum Coverage: Human Amyloid Imaging 2013 Solanezumab Selected for Alzheimer’s A4 Prevention Trial HAI—Spotlight on Tau Tracers at Human Amyloid Imaging Meeting HAI—Amyloid Imaging in the ...
Shape-shifting cells may explain why APOE4 carriers are at greater risk of cerebrovascular disease. In the 24 September Cell, scientists led by Joel Blanchard at the Icahn School of Medicine at Mount ...
During ARIA, immune cells march from blood to brain. What sparks this mobilization? Scientists led by Moustafa Algamal, Mariel Kozberg, and Brian Bacskai at Mass General Brigham investigated this ...
Scientists show off new ways to biochemically probe tiny pieces of brain tissue taken from living people. In the September 24 Nature Communications, Ross Paterson and Aram Aslanyan at University ...
Amyotrophic lateral sclerosis is brutal. Familial mutations cause about one in 10 cases, of which fewer than 1 percent are due to an autosomal-dominant mutation in CHCHD10. Yet one carrier of a ...
The National Alzheimer’s Coordinating Center unites the collections of the neuropathology cores at 27 NIA-funded AD Research Centers into a single database. It contains records on 13,000 brains, 3,000 ...
Low dose interleukin 2 is being tested as an immunomodulatory approach in neurodegenerative diseases. It increases the number and activity of regulatory T cells (Tregs) that suppress inflammation. At ...
27 – 30 June 2026 DOWNLOAD TO YOUR CALENDAR Minneapolis, Minnesota View Conference Website ...
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