Researchers have developed shotgun genetic engineering, a multiplexed strategy that screens millions of combinatorial genetic designs in mammalian cells within a single experiment.

A comparative study of mouse germ cell promoters finds the Ldhc promoter drives the strongest and most reliable transgene ...

How readily a cell divides and how well it survives are fundamental to life, shaping everything from organ size to the body's ability to withstand disease. That combination, known as cell fitness, isn ...

Scientists have identified thousands of genetic differences that change a person's risk of disease, but working out how they ...

In prokaryotic cells, transcription (DNA to mRNA) and translation (mRNA to protein) are so closely linked that translation ...

Investigating context-specific genetic associations can lead to deeper understanding of the biological mechanisms underlying human traits. With this cross-journal Collection, the editors at Nature ...

There are hundreds of cell types in the human body, each with a specific role spelled out in their DNA. In theory, all it takes for cells to behave in desired ways—for example, getting them to produce ...

A multi-institutional study led by researchers at UNC Lineberger Comprehensive Cancer Center, the Salk Institute for Biological Studies, and UC San Diego has uncovered new genetic rules that determine ...

New work by Columbia researchers has turned a textbook principle of genetics on its head and revealed why some people who carry disease-causing genes experience no symptoms. Every biology student ...

Add Yahoo as a preferred source to see more of our stories on Google. Photo Credit: iStock Scientists have cleared a striking hurdle in synthetic biology: They got two different genetic codes working ...

UCLA researchers grew brain cells from dozens of genetically distinct donors together in a cell village, then built a statistical tool called Townlet to measure each donor's cell fitness — how well ...