Background Chronic activation of the hypothalamic–pituitary–adrenal axis due to long-term stress, reflected by elevated hair ...

Carbon emissions and environmental pollutants are responsible for deaths, property damage and reduction in population health ...

Background Heart-type fatty acid-binding protein (H-FABP), a principal intracellular transporter of long-chain fatty acids ...

Atrial fibrillation (AF) and coronary artery disease (CAD) are prevalent cardiovascular disorders that increasingly coexist as populations age and cardiometabolic comorbidities rise. Their ...

Background Drug-coated balloon (DCB) angioplasty has emerged as a potential stent-free strategy for percutaneous coronary intervention (PCI) in de novo coronary artery disease, but robust randomised ...

Cancer therapy has dramatically changed over the past many decades, not only in efficacy but also complexity, with targeted therapeutics that have novel mechanisms of action. As a direct result of ...

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Background Double sequential defibrillation (DSD) is a promising treatment for patients with out-of-hospital cardiac arrest (OHCA) with refractory ventricular fibrillation. The reproducibility and ...

Cardiovascular disease (CVD) accounts for a third of all deaths, making it the leading cause of mortality globally. Coronary microvascular dysfunction (CMD) has emerged as a prominent condition in ...

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia worldwide and is associated with substantial morbidity and mortality, imposing a significant burden on patients and healthcare ...

Background Residual left ventricular (LV) hypertrophy and incomplete reverse remodelling after transcatheter aortic valve replacement (TAVR) are associated with adverse outcomes. Whether ...

Sleep breathing disorders (SBDs)—including obstructive sleep apnoea, central sleep apnoea and sleep-related hypoventilation syndromes—represent a major yet under-recognised contributor to global ...