Screening ionisable lipids with a gene-editor-sized RNA identified LC-1, an LNP component that retained potency as cargo ...

Incyte will share updated clinical single-cell data characterizing its calreticulin-targeted therapy for myeloproliferative ...

Researchers in Germany have identified a SOX9-responsive regulatory route to IRF6, a major orofacial-cleft risk gene, in ...

Sofi-cel is an allogeneic, off-the-shelf, CD7-targeted CAR-T cell therapy being developed for T-cell cancers. Allotera uses ...

Ole Bock moderated two sessions at the Chinese Society of Cell & Gene Therapy Annual Meeting in Beijing, and CMN received the ...

CMN founder Jens-Ole Bock will moderate a panel discussion at CSGCT 2026 in Beijing on 20 September on the question that now defines the field: with the first in vivo CRISPR therapy under FDA priority ...

Delivering a CRISPR-Cas-derived adenine base editor as a short-lived protein-guide RNA complex enabled efficient PCSK9 editing while human embryos developed to blastocysts. By contrast, mRNA delivery ...

A gene-edited pig kidney kept a patient with end-stage kidney disease dialysis-free for 271 days, then failed and was removed without leaving the recipient sensitised against human donors. Eighty-two ...

Naturally occurring loss-of-function variants in ANGPTL3 are associated with low triglycerides, low LDL cholesterol and reduced atherosclerotic cardiovascular risk – a genotype CTX310 sets out to ...

Phase 1 study in patients with mCRPC expected to begin enrollment in the fourth quarter of 2026 REDWOOD CITY, Calif.--(BUSINESS WIRE)--Adicet Bio, Inc. (Nasdaq: ACET), a clinical stage biotechnology ...

Wave Life Sciences has reached alignment with the US Food and Drug Administration on a registrational pathway for WVE-006, a GalNAc-conjugated RNA... Genome Editing Exposes Alfalfa’s Drought-Control..

Nature Communications study finds UNCOVERseq™ delivered the strongest combined sensitivity and precision among evaluated CRISPR off-target nomination methods Findings provide a more rigorous framework ...